Low-Fat Pizza Casserole Recipe

This low fat pizza casserole brings all the bold, cheesy flavors of a slice of pepperoni pizza—without the grease. Made with lean ground turkey, plenty of vegetables, and melty reduced-fat cheese, it’s a fun, family-friendly dinner that’s big on flavor and light on fat. Each hearty serving clocks in at just 6 grams of fat, making it a perfect pick for low-fat, high-protein, and calorie-conscious meal plans.

About This Recipe

You’ll taste layers of saucy tomato, seasoned meat, savory veggies, and melted cheese—all nestled into tender whole wheat pasta. It has that gooey, indulgent feel of pizza night but with a clean, satisfying finish. Think of it as pizza’s lighter, cozier cousin.

What makes this even better? It’s fast, freezer-friendly, and totally customizable. Whether you’re feeding picky eaters or looking to meal prep a week of healthy lunches, this one-pan wonder delivers.

Why This Recipe Belongs in Your Diet

Using extra lean ground turkey and reduced-fat cheese cuts saturated fat without losing the savory flavor you expect from pizza. Whole wheat pasta and veggies boost fiber, while a homemade sauce keeps sodium and calories in check. This is comfort food that supports your goals.

What You’ll Need (Ingredients)

We’re turning your favorite pizza toppings into a wholesome, casserole-style dinner with lean swaps and classic flavors.

• 1 pound 93% lean ground turkey: A lighter alternative to ground beef or sausage.
• 1 small onion, diced: Adds natural sweetness and depth.
• 1 green bell pepper, diced: Brings crunch and color.
• 1/2 teaspoon dried oregano: For classic pizza flavor.
• 1/4 teaspoon garlic powder: Adds a savory boost without fat.
• 1/4 teaspoon black pepper: Balances the richness.
• 1/2 teaspoon salt: Just enough to season the dish.
• 1 (15 oz) can no-salt-added tomato sauce: The base of our homemade pizza sauce.
• 1 tablespoon tomato paste: Deepens the flavor of the sauce.
• 1 teaspoon balsamic vinegar: Adds a subtle tang, like pizza sauce from scratch.
• 2 cups cooked whole wheat rotini or penne: A high-fiber, filling base.
• 1/2 cup plain nonfat Greek yogurt: Adds creamy texture without cream.
• 1/2 cup reduced-fat shredded mozzarella cheese: Melty topping with less fat.
• Optional: 8 slices turkey pepperoni, chopped: Adds a pop of flavor with minimal fat.

How to Make Low Fat Pizza Casserole

1. Preheat oven to 375°F (190°C). Lightly spray a 9×9-inch baking dish with cooking spray.
2. Cook turkey, onion, and bell pepper in a skillet over medium heat for 6–8 minutes until meat is browned and veggies are soft. Drain any liquid.
3. Add oregano, garlic powder, pepper, and salt, stir for 1 minute to toast the spices.
4. Stir in tomato sauce, tomato paste, and vinegar. Let simmer for 2–3 minutes to thicken slightly.
5. Remove from heat, then stir in Greek yogurt until creamy.
6. Add cooked pasta and chopped turkey pepperoni (if using). Mix everything together.
7. Transfer to baking dish, top with shredded mozzarella.
8. Bake uncovered for 20–25 minutes until hot and bubbly. Let cool slightly before serving.

Recipe Tips and Variations

• Add chopped mushrooms or olives for more of that pizza shop flavor.
• Make it spicy with crushed red pepper or diced jalapeños.
• Swap in cooked quinoa or cauliflower rice for a lower-carb option.
• Sprinkle with fresh basil or parsley before serving for a fresh finish.

How to Store Leftovers

Let cool completely, then store in an airtight container in the fridge for up to 4 days. You can freeze single portions for up to 2 months. Reheat in the microwave or oven until warmed through.

Nutrition Facts

• Serving Size: 1 cup
• Calories: 300 kcal
• Fat: 6 g
• Carbohydrates: 27 g
• Protein: 27 g
• Sodium: 420 mg