Low-Fat Chicken Pot Pie Casserole Recipe

This low-fat chicken pot pie casserole captures the soul-warming essence of traditional pot pie but slashes the fat to just 6 grams per serving. You still get all the creamy, savory goodness, tender chicken, and hearty vegetables just without the buttery crust. This healthy comfort food is perfect if you’re looking for a low-fat, high-protein, and family-friendly meal that tastes indulgent but keeps things light.

About This Recipe

Each bite of this casserole is loaded with lean chicken, sweet peas and carrots, and a velvety sauce that mimics a classic pot pie filling. The top is finished with a light layer of flaky, golden biscuits made from low-fat Greek yogurt and whole wheat flour for a wholesome twist. It’s comforting without being heavy, with just the right balance of creamy and crusty.

It’s a practical, all-in-one meal that’s ideal for busy weeknights. You can assemble it in advance, or even freeze it before baking. It’s the kind of dish that gets rave reviews at the dinner table, no matter the diet.

Why This Recipe Belongs in Your Diet

Swapping heavy cream and butter for nonfat Greek yogurt and reduced-fat cream of chicken soup creates a creamy base with far less fat and more protein. The biscuit topping made with whole wheat flour and yogurt adds fiber and keeps the fat low, turning this classic comfort food into a smart, satisfying dinner.

What You’ll Need (Ingredients)

This pot pie-inspired casserole uses simple, wholesome ingredients and a few clever swaps to stay low in fat while full of flavor.

• Cooked Chicken Breast (2 cups, chopped): Lean, skinless breast keeps this filling and light.
• Frozen Mixed Vegetables (1½ cups): Classic pot pie flavor from peas, carrots, corn, and green beans.
• Reduced-Fat Cream of Chicken Soup (1 can, 10.5 oz): Adds creamy texture and depth without the fat.
• Plain Nonfat Greek Yogurt (¾ cup): Adds creaminess and body with extra protein.
• Garlic Powder (1 teaspoon): Enhances the savory base without added calories.
• Onion Powder (1 teaspoon): Adds a slow-cooked flavor shortcut.
• Dried Thyme (½ teaspoon): Gives that warm, comforting pot pie flavor.
• Salt (½ teaspoon): Helps bring out all the other flavors.
• Black Pepper (¼ teaspoon): A little bit of bite to balance the creaminess.

For the Biscuit Topping:

• White Whole Wheat Flour (1 cup): Lighter than regular whole wheat but still rich in fiber.
• Baking Powder (1½ teaspoons): Helps the biscuits rise.
• Salt (¼ teaspoon): Balances the flavor of the topping.
• Plain Nonfat Greek Yogurt (¾ cup): The secret to moist, tender low-fat biscuits.

How to Make Low Fat Chicken Pot Pie Casserole

1. Preheat the oven to 400°F and lightly spray an 8×8-inch or 9×9-inch baking dish.
2. In a large bowl, mix the cream of chicken soup, yogurt, garlic powder, onion powder, thyme, salt, and pepper until smooth.
3. Stir in the chicken and vegetables, mixing until everything is coated.
4. Spread the mixture evenly in your prepared baking dish.
5. Make the biscuit topping by mixing the flour, baking powder, and salt in a bowl. Stir in the Greek yogurt until a dough forms.
6. Drop spoonfuls of the dough over the chicken mixture, flattening slightly to cover most of the surface.
7. Bake for 25–30 minutes, or until the filling is bubbly and the biscuit topping is lightly golden and cooked through.
8. Let it rest for 5 minutes before serving.

Recipe Tips and Variations

• Add fresh herbs like parsley or chives for a flavor boost.
• Mix in sautéed mushrooms or onions for extra depth.
• For a gluten-free version, use a gluten-free biscuit mix and certified GF soup.
• Want more texture? Add a sprinkle of reduced-fat shredded cheese under the biscuit topping.

How to Store Leftovers

Refrigerate leftovers in an airtight container for up to 4 days. You can also freeze the whole casserole before baking or after—it reheats beautifully in the oven or microwave.

Nutrition Facts

• Serving Size: 1 cup
• Calories: 295 kcal
• Fat: 6 g
• Carbohydrates: 26 g
• Protein: 28 g
• Sodium: 530 mg

Try More Recipes:

• Low-Fat Chicken Noodle Casserole Recipe
• Low-Fat Chicken Divan Casserole Recipe
• Low-Fat Chicken Cordon Bleu Casserole Recipe